Super HN

New Show
   John Hopkins: taking Tylenol during pregnancy associated with Autism ADHD (2019) (hub.jhu.edu)
Here’s a comment I made in a different thread—

> It occurs to me that pain killers can cross the placenta and also affect gut microbes, and that since sometimes autism isn’t inherited, there’s a gut microbe imbalance component to autism that needs more attention, especially related to how gut microbes differ in those born with and without Caesarians. Secondly, how are genes related to autism also linked to the gut-brain axis.

> I believe acetaminophen is prescribed routinely during pregnancy because it’s considered safe to use, but it’s indicated that there may be a link between its use and outcomes, https://pmc.ncbi.nlm.nih.gov/articles/PMC9385573/

> Here’s some additional information from another paper

>> The gut microbiome has been implicated in the pathophysiological mechanisms of ADHD through the MGBA. Alterations in the MGBA contribute to neuroinflammation and oxidative stress, leading to ADHD core symptoms and associated comorbidities such as sleep disturbances. There is some evidence indicating maternal stress and the use of acetaminophen, which is a common pain reliever and fever reducer, may increase the risk of ADHD in offspring during pregnancy https://www.mdpi.com/2075-1729/14/10/1234