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421. The Eleven-Faced Die That Emulates Two Six-Sided Dice
422. OpenAI won't make money by 2030 and needs another $207B, HSBC estimates
What company has a consumer base representing 44% of the world’s adult population and a $620 billion data center bill? OpenAI five years from now.
423. Study Reveals How Tattoo Ink Affects the Immune System
424. Cardiac implantable electronic devices' longevity: A novel modelling tool
Aims Generator longevity is the key issue for patients, and is also important for payers, yet implanters of Cardiac Implantable Electronic Devices (CIEDs) face a challenge when selecting the appropriate device since battery longevity is only known for previous generation devices and whilst projected longevities are available for current devices, these are not in comparable formats. This study presents a new framework that facilitates an estimation of longevities for all CIEDs of both previous and existing generations that could simplify personalization of the device choice. Methods Longevity can be calculated based upon a simple concept entitled the “power consumption index” (PCI = t x I/C, where t is a constant of 1 hour, I is the current required by the device and C, its battery capacity). We retrieved published data from the user manuals of all commonly used pacemakers including single chamber, dual chamber, cardiac resynchronization and leadless devices. C and the components of current I including background current (Ibackground) and the pacing current (Ipacing) were calculated prior to calculation of the PCI for each device. Subsequently, a set of fictitious patient pool conditions via a Monte-Carlo simulation were used to model CIED survival curves which were then compared with real-life data from the Swedish device registry of previous generation CIEDs. Finally, we modeled survival curves for current generation devices using the PCI model. Results Using the PCI approach we were able to calculate longevities for all pacemaker devices under a variety of settings. The modeled Ibackground matched the data reported by manufacturers, and, under a variety of settings, regression analysis showed a low average error rate between industry-reported and modelled longevities (ratio: modelled longevity/industry reported longevity −1) = 0.1 ± 4.0% and 0.1 ± 0.7% for previous and existing SR/DR devices, 1.0 ± 5.0% and 0 ± 3.0% for previous and existing CRT-P, and 0 ± 4.0% for leadless pacemakers, respectively). More than 50% of the PCI and thereby a significant contributor to longevity was accounted for by Ibackground. Ipacing was the second largest contributor (20% for standard single and dual chamber devices, 30% for CRT-P and 40% for leadless devices). Certain pacing algorithms and IEGM storage considerably impacted specific devices with longevity losses of up to 1 year. The Monte-Carlo analysis demonstrated consistency between projected longevities by the PCI model and real-life data for historical devices and the calculated longevities that stemmed from this were consistent with the real-world data from Sweden. Conclusion The PCI model combining power consumption and battery capacity allows a comparison of longevity across CIEDs and programming options. Such a tool could help implanters improve personalization of device prescription for their patients and payers to make more informed decisions about tailoring device purchases and programming most appropriate for their population.
425. Why 90s Movies Feel More Alive Than Anything on Netflix
Tags: #Blogging #ClassicCinema #ModernMovies #Netflix #Streaming I was rewatching The Silence of the Lambs the other night, and somethin...
426. Downsampling: Largest-Triangle-Three-Buckets and the Fourier Transform
427. Reddit Migrates Comment Back End from Python to Go
428. Someone Is Trying to 'Hack' People Through Apple Podcasts
For months Apple Podcasts has been randomly opening spirituality and religion podcasts by itself, and in one case directing listeners to a potentially malicious website.
429. Tom Stoppard, Award-Winning Playwright of Witty Drama, Dies at 88
430. Agent Design Is Still Hard
My Agent abstractions keep breaking somewhere I don’t expect.
431. Superman copy found in mum's attic is most valuable comic ever at $9.12M
It's a bird! It's a plane! It's a new record after Man of Steel comic found in a California home is auctioned.
432. Implementing Drift Search with Neo4j and LlamaIndex
Learn how to avoid the computational overhead of processing all community reports while still maintaining comprehensive coverage.
433. Using Antigravity for Statistical Physics in JavaScript
Testing Google's new IDE and top model on a ferromagnetic simulation
434. Amazon unveils Starlink rival capable of up to 1 Gbps satellite internet
Amazon has unveiled Leo Ultra, a high-throughput phased-array terminal for its upcoming satellite internet service, now rebranded from Project Kuiper to Amazon Leo.
435. Why Strong Consistency?
436. Don't Download Apps
The personal blog of Caleb Jay Rogers, Software Engineer